9/12/2023 0 Comments 2d 4d ratio pubmedTherefore, the inclusion of personality measures to study the link between the digit ratio and schizophrenia might help to provide insights in a potential continuum from healthy to schizophrenic behavior.ĭigit ratio Personality SPQ Schizophrenia.Ĭopyright © 2014 Elsevier B.V. The 2D:4DL had an ICC of r 0.996 (95CI 0.9940.998), while the right 2D:4D ratio ICC was r 0.984 (95CI 0.9800.989), The other anthropometric variables weight and height were measured. Same results were observed for the digit ratio of the left hand and the SPQ in the healthy total and healthy female subsample. However, a positive association between right 2D:4D ratio and schizotypal personality traits was found in healthy controls (both in the male and female subsamples) suggesting that a high 2D:4D ratio could represent a vulnerability factor for schizophrenia in healthy males and females. No significant difference between cases and controls in 2D:4D ratios for both hands could be observed. Moreover, we investigated the link between 2D:4D ratios and schizotypal personality traits in the participants of the study. In the current study, we tried to replicate the result of this study on the 2D:4D ratio in schizophrenia patients and controls in a Chinese sample. (2010) examined 2D:4D ratios in Asian patients with schizophrenia and found an increased 2D:4D pattern in male patients compared to male healthy controls. In this context, the ratio of the index finger to ring finger length (2D:4D) has been put forward as an indicator of the intrauterine sex hormonal level. Prenatal estrogen/testosterone exposure is known to be involved in early brain development.
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